I have pure silver cables (DIY) and copper cables. There is no difference using these cables with the Mainline vs other amps.
If you are asking about silver vs copper cables, that's a whole difference discussions. Theoretically there should be no difference between well made cables with either metal. In practice, some cables may sound difference. remember, a cable cannot make the sound better. A cable can only degrade the sound. Different cables might degrade the sound differently, and at different frequencies. A passive cable cannot add anything.